Insider Trading disclosures for Vir Biotechnology Inc

The latest disclosure was made by Vanina de Verneuil in Vir Biotechnology Inc where a trade of 7,373 Common Stock done at an average price of $9.1 was reported to US exchanges on Feb. 26, 2025.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name	Client Category	Action	Reported to Exchange	Quantity	Post Transaction Holding	Traded %	Avg. Price	Value	Security Type
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 9.14 per share.	26 Feb 2025	7,373	79,460 (0%)	0%	9.1	67,402	Common Stock
George A. Scangos	Director	Sale of securities on an exchange or to another person at price $ 9.45 per share.	24 Feb 2025	10,056	698,239 (0%)	0%	9.5	95,063	Common Stock
Ann M. Hanly	EVP & Chief Technology Officer	Sale of securities on an exchange or to another person at price $ 9.45 per share.	24 Feb 2025	14,168	117,901 (0%)	0%	9.5	133,936	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Sale of securities on an exchange or to another person at price $ 9.45 per share.	22 Feb 2025	16,122	849,217 (0%)	0%	9.5	152,408	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	240,000	865,339 (0%)	0%		0	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	480,000	480,000	-		-	Stock Option (Right to Buy)
Brent Sabatini	SVP, Chief Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	40,000	40,000	-		-	Stock Option (Right to Buy)
Brent Sabatini	SVP, Chief Accounting Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	20,000	48,189 (0%)	0%		0	Common Stock
Brent Sabatini	SVP, Chief Accounting Officer	Sale of securities on an exchange or to another person at price $ 9.45 per share.	22 Feb 2025	1,562	46,627 (0%)	0%	9.5	14,766	Common Stock
Vanina de Verneuil	EVP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	70,000	70,000	-		-	Stock Option (Right to Buy)
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 9.45 per share.	22 Feb 2025	5,140	86,833 (0%)	0%	9.5	48,590	Common Stock
Vanina de Verneuil	EVP and General Counsel	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2025	35,000	91,973 (0%)	0%		0	Common Stock
George A. Scangos	Director	Sale of securities on an exchange or to another person at price $ 9.81 per share.	18 Feb 2025	10,964	708,295 (0%)	0%	9.8	107,575	Common Stock
Brent Sabatini	SVP, Chief Accounting Officer	Sale of securities on an exchange or to another person at price $ 9.15 per share.	13 Feb 2025	1,562	28,189 (0%)	0%	9.1	14,291	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 12.52 per share.	08 Jan 2025	10,960	1,312,391 (1%)	0%	12.5	137,219	Common Stock
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 8.22 per share.	02 Dec 2024	76	56,973 (0%)	0%	8.2	625	Common Stock
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 10.11 per share.	06 Nov 2024	4,397	56,973 (0%)	0%	10.1	44,454	Common Stock
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 9.47 per share.	01 Nov 2024	2,347	61,370 (0%)	0%	9.5	22,225	Common Stock
Vanina de Verneuil	EVP and General Counsel	Sale of securities on an exchange or to another person at price $ 7.20 per share.	01 Nov 2024	1,403	63,717 (0%)	0%	7.2	10,107	Common Stock
George A. Scangos	Director	Other type of transaction at price $ 0.00 per share.	23 Oct 2024	598,270	598,270 (0%)	0%		0	Common Stock
George A. Scangos	Director	Other type of transaction at price $ 0.00 per share.	23 Oct 2024	598,270	719,259 (0%)	0%		0	Common Stock
George A. Scangos	Director	Other type of transaction at price $ 0.00 per share.	23 Oct 2024	598,270	1,151,730 (1%)	0%		0	Common Stock
George A. Scangos	Director	Other type of transaction at price $ 0.00 per share.	23 Oct 2024	598,270	1,151,730 (1%)	0%		0	Common Stock
Janet Napolitano	Director	Sale of securities on an exchange or to another person at price $ 7.80 per share.	09 Sep 2024	12,190	11,616 (0%)	0%	7.8	95,032	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Other type of transaction at price $ 0.00 per share.	12 Jun 2024	53,118	625,339 (0%)	0%		0	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Other type of transaction at price $ 0.00 per share.	12 Jun 2024	53,118	53,118 (0%)	0%		0	Common Stock
Saira Ramasastry	Director	Sale of securities on an exchange or to another person at price $ 10.95 per share.	11 Jun 2024	4,000	14,619 (0%)	0%	10.9	43,789	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	23,806 (0%)	0%		0	Common Stock
George A. Scangos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
George A. Scangos	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	120,989 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	584,148 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	46,683 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	1,323,351 (1%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	18,619 (0%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	23,806 (0%)	0%		0	Common Stock
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	30 May 2024	8,000	23,806 (0%)	0%		0	Common Stock
Norbert W. Bischofberger	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Norbert W. Bischofberger	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Norbert W. Bischofberger	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000 (0%)	0%		0	Common Stock
Ramy Farid	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000 (0%)	0%		0	Common Stock
Ramy Farid	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Ramy Farid	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	29 May 2024	16,000	16,000	-		-	Stock Option (Right to Buy)
Marianne De Backer	Director, Chief Executive Officer	Sale of securities on an exchange or to another person at price $ 9.46 per share.	03 Apr 2024	72,995	678,457 (0%)	0%	9.5	690,365	Common Stock
Ann M. Hanly	EVP & Chief Technology Officer		01 Apr 2024	2,711	132,069 (0%)	0%	10.1	27,251	Common Stock
Sung H. Lee	EVP & Chief Financial Officer	Sale of securities on an exchange or to another person at price $ 9.89 per share.	27 Mar 2024	6,008	100,492 (0%)	0%	9.9	59,404	Common Stock
Marianne De Backer	Director, Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2024	175,000	751,452 (0%)	0%		0	Common Stock
De Backer Marianne	Director, Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2024	350,000	350,000	-		-	Stock Option (Right to Buy)
Lee H. Sung	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2024	40,000	106,500 (0%)	0%		0	Common Stock
A. George Scangos	Director	Sale of securities on an exchange or to another person at price $ 11.65 per share.	22 Feb 2024	17,722	112,989 (0%)	0%	11.7	206,522	Common Stock
H. Sung Lee	EVP & Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2024	80,000	80,000	-		-	Stock Option (Right to Buy)
Ann Hanly M.	EVP & Chief Technology Officer		22 Feb 2024	32,500	147,076 (0%)	0%		0	Common Stock
Ann Hanly M.	EVP & Chief Technology Officer		22 Feb 2024	65,000	65,000	-		-	Stock Option (Right to Buy)
Hanly Ann M.	EVP & Chief Technology Officer		22 Feb 2024	12,296	134,780 (0%)	0%	10.0	123,521	Common Stock
Scangos A. George	Director	Sale of securities on an exchange or to another person at price $ 10.05 per share.	22 Feb 2024	10,028	130,711 (0%)	0%	10.0	100,737	Common Stock
Pang Phil	EVP & Chief Medical Officer	Sale of securities on an exchange or to another person at price $ 10.24 per share.	16 Feb 2024	3,321	264,679 (0%)	0%	10.2	34,006	Common Stock
A. George Scangos	Director	Sale of securities on an exchange or to another person at price $ 10.24 per share.	16 Feb 2024	10,878	157,611 (0%)	0%	10.2	111,386	Common Stock
Scangos George A.	Director	Sale of securities on an exchange or to another person at price $ 10.22 per share.	16 Feb 2024	16,872	140,739 (0%)	0%	10.2	172,385	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 24.66 per share.	30 Jun 2023	18,000	1,315,351 (1%)	0%	24.7	443,916	Common Stock
Saira Ramasastry	Director	Sale of securities on an exchange or to another person at price $ 25.67 per share.	01 Jun 2023	3,500	10,619 (0%)	0%	25.7	89,845	Common Stock
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 25.67 per share.	01 Jun 2023	2,500	106,840 (0%)	0%	25.7	64,175	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	15,806 (0%)	0%		0	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	121,174 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	576,148 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	45,088 (0%)	0%		0	Common Stock
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	15,806 (0%)	0%		0	Common Stock
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	1,333,351 (1%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	14,119 (0%)	0%		0	Common Stock
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	15,806 (0%)	0%		0	Common Stock
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	12,054	12,054	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 May 2023	6,027	15,806 (0%)	0%		0	Common Stock
Marianne De Backer	Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Apr 2023	576,452	576,452 (0%)	0%		0	Common Stock
Marianne De Backer	Chief Executive Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	03 Apr 2023	1,152,904	1,152,904	-		-	Stock Option (Right to Buy)
Ann M. Hanly	Chief Technology Officer		30 Mar 2023	2,627	114,576 (0%)	0%	22.8	59,817	Common Stock
Sung H. Lee	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Mar 2023	133,000	133,000	-		-	Stock Option (Right to Buy)
Sung H. Lee	Chief Financial Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	27 Mar 2023	66,500	66,500 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 22.59 per share.	08 Mar 2023	17,935	1,327,324 (1%)	0%	22.6	405,062	Common Stock
Johanna Friedl-Naderer	EVP & Chief Operating Officer	Sale of securities on an exchange or to another person at price $ 22.82 per share.	03 Mar 2023	1,482	148,518 (0%)	0%	22.8	33,819	Common Stock
Elliott Sigal	Director	Purchase of securities on an exchange or from another person at price $ 22.73 per share.	01 Mar 2023	2,500	10,000 (0%)	0%	22.7	56,816	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 25.97 per share.	23 Feb 2023	12,631	183,608 (0%)	0%	26.0	328,065	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 22.74 per share.	23 Feb 2023	4,239	179,369 (0%)	0%	22.7	96,382	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 23.56 per share.	23 Feb 2023	10,880	168,489 (0%)	0%	23.6	256,300	Common Stock
Howard Horn	CFO	Sale of securities on an exchange or to another person at price $ 25.97 per share.	23 Feb 2023	2,248	230,712 (0%)	0%	26.0	58,387	Common Stock
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2023	73,000	110,209 (0%)	0%		0	Common Stock
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2023	46,000	46,000	-		-	Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 25.97 per share.	22 Feb 2023	1,795	108,414 (0%)	0%	26.0	46,622	Common Stock
Ann M. Hanly	Chief Technology Officer		22 Feb 2023	37,500	119,505 (0%)	0%		0	Common Stock
Ann M. Hanly	Chief Technology Officer		22 Feb 2023	55,000	55,000	-		-	Stock Option (Right to Buy)
Ann M. Hanly	Chief Technology Officer		22 Feb 2023	2,302	117,203 (0%)	0%	26.0	59,790	Common Stock
Johanna Friedl-Naderer	EVP & Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2023	60,000	150,000 (0%)	0%		0	Common Stock
Johanna Friedl-Naderer	EVP & Chief Operating Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2023	70,000	70,000	-		-	Stock Option (Right to Buy)
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	49,984	111,644 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 28.80 per share.	17 Feb 2023	6,474	196,239 (0%)	0%	28.8	186,451	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 28.02 per share.	17 Feb 2023	11,382	202,713 (0%)	0%	28.0	318,867	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 25.29 per share.	17 Feb 2023	9,894	214,095 (0%)	0%	25.3	250,199	Common Stock
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	64,930	179,930 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	64,930	3,533,629 (3%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	49,984	111,644 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	49,984	827,151 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Other type of transaction at price $ 0.00 per share.	17 Feb 2023	49,984	827,151 (0%)	0%		0	Common Stock
Howard Horn	CFO	Sale of securities on an exchange or to another person at price $ 25.29 per share.	17 Feb 2023	2,424	232,960 (0%)	0%	25.3	61,298	Common Stock
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 25.29 per share.	17 Feb 2023	1,981	37,209 (0%)	0%	25.3	50,096	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 28.35 per share.	08 Feb 2023	17,288	1,345,886 (1%)	0%	28.4	490,160	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 29.00 per share.	08 Feb 2023	627	1,345,259 (1%)	0%	29	18,183	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 25.83 per share.	09 Jan 2023	17,915	1,363,174 (1%)	0%	25.8	462,784	Common Stock
Elliott Sigal	Director	Purchase of securities on an exchange or from another person at price $ 24.96 per share.	05 Jan 2023	2,500	7,500 (0%)	0%	25.0	62,396	Common Stock
Elliott Sigal	Director	Purchase of securities on an exchange or from another person at price $ 25.60 per share.	03 Jan 2023	2,500	2,500 (0%)	0%	25.6	63,993	Common Stock
Elliott Sigal	Director	Purchase of securities on an exchange or from another person at price $ 25.25 per share.	03 Jan 2023	2,500	5,000 (0%)	0%	25.3	63,136	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 25.81 per share.	08 Dec 2022	17,915	1,381,089 (1%)	0%	25.8	462,366	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 27.38 per share.	08 Nov 2022	17,915	1,399,004 (1%)	0%	27.4	490,549	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 20.67 per share.	10 Oct 2022	17,915	1,416,919 (1%)	0%	20.7	370,278	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 21.90 per share.	08 Sep 2022	17,915	1,434,834 (1%)	0%	21.9	392,335	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	239,559	5,626,008 (5%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	1,508	32,043 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	24,737	539,883 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	196,003	5,865,567 (5%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	253,997	7,601,096 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	1,850	33,893 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	30,238	570,121 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Sep 2022	310,441	7,290,655 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	282,219	8,137,312 (7%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	1,684	30,535 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	27,489	515,146 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	282,219	7,855,093 (7%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	217,781	6,061,570 (5%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	1,684	28,851 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	27,489	487,657 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Aug 2022	217,781	6,279,351 (5%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	282,219	8,701,750 (7%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	1,684	27,167 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	27,489	460,168 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	282,219	8,419,531 (7%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	217,781	6,497,132 (5%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	1,684	25,483 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	27,489	432,679 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	24 Aug 2022	217,781	6,714,913 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	18 Aug 2022	282,219	8,983,969 (8%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	18 Aug 2022	1,684	23,799 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	18 Aug 2022	27,489	405,190 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	18 Aug 2022	217,781	6,932,694 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	217,781	7,586,037 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	1,684	22,115 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	27,489	377,701 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	282,219	9,266,188 (8%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	217,781	7,150,475 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	1,684	20,431 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	27,489	350,212 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	282,219	9,548,407 (8%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	217,781	7,368,256 (6%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	1,684	18,747 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	27,489	322,723 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	12 Aug 2022	282,219	9,830,626 (8%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	09 Aug 2022	70,177	254,584 (0%)	0%	1.5	107,371	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Aug 2022	7,916	125,416	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Aug 2022	70,177	140,328	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 10.40 per share.	09 Aug 2022	7,916	262,500 (0%)	0%	10.4	82,287	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 30.29 per share.	08 Aug 2022	17,915	1,452,749 (1%)	0%	30.3	542,685	Common Stock
Saira Ramasastry	Director	Sale of securities on an exchange or to another person at price $ 30.00 per share.	11 Jul 2022	5,000	8,092 (0%)	0%	30	150,000	Common Stock
Saira Ramasastry	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	11 Jul 2022	5,000	42,777	-		-	Stock Option (Right to Buy)
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 12.76 per share.	11 Jul 2022	5,000	13,092 (0%)	0%	12.8	63,800	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 29.57 per share.	08 Jul 2022	5,072	1,470,664 (1%)	0%	29.6	149,960	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 28.87 per share.	08 Jul 2022	12,843	1,475,736 (1%)	0%	28.9	370,734	Common Stock
Robert J. More	Director	Other type of transaction at price $ 0.00 per share.	09 Jun 2022	3,374	489,485 (0%)	0%		0	Common Stock
Robert J. More	Director	Other type of transaction at price $ 0.00 per share.	09 Jun 2022	3,374	39,061 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 26.51 per share.	08 Jun 2022	500	1,488,579 (1%)	0%	26.5	13,255	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 25.82 per share.	08 Jun 2022	17,415	1,489,079 (1%)	0%	25.8	449,721	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Jun 2022	282,219	10,395,064 (9%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Jun 2022	29,173	283,124 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	02 Jun 2022	217,781	8,021,599 (7%)	0%		0	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	9,779 (0%)	0%		0	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	115,147 (0%)	0%		0	Common Stock
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	253,951 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	42,435 (0%)	0%		0	Common Stock
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	9,779 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	1,509,868 (1%)	0%		0	Common Stock
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 23.82 per share.	23 May 2022	3,374	1,506,494 (1%)	0%	23.8	80,369	Common Stock
Saira Ramasastry	Director	Sale of securities on an exchange or to another person at price $ 23.82 per share.	23 May 2022	1,687	8,092 (0%)	0%	23.8	40,184	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	9,779 (0%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	9,779 (0%)	0%		0	Common Stock
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	6,405	9,779 (0%)	0%		0	Common Stock
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	23 May 2022	12,810	12,810	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 20.62 per share.	09 May 2022	14,541	1,503,463 (1%)	0%	20.6	299,835	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 21.49 per share.	28 Apr 2022	3,822	1,518,004 (1%)	0%	21.5	82,135	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 20.74 per share.	28 Apr 2022	14,093	1,521,826 (1%)	0%	20.7	292,289	Common Stock
Ann M. Hanly	Chief Technology Officer		30 Mar 2022	2,627	81,473 (0%)	0%	26.2	68,925	Common Stock
George A. Scangos	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	10 Mar 2022	111,000	223,989 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	10 Mar 2022	222,000	222,000	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	10 Mar 2022	9,000	184,407 (0%)	0%	1.5	13,770	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Mar 2022	9,000	210,505	-		-	Stock Option (Right to Buy)
Johanna Friedl-Naderer	Chief Business Officer, Global	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2022	45,000	45,000	-		-	Stock Option (Right to Buy)
Johanna Friedl-Naderer	Chief Business Officer, Global	Grant, award, or other acquisition of securities at price $ 0.00 per share.	02 Mar 2022	90,000	90,000 (0%)	0%		0	Common Stock
Howard Horn	CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	50,000	50,000	-		-	Stock Option (Right to Buy)
Howard Horn	CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	35,000	235,384 (0%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Feb 2022	1,375	219,505	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	70,000	70,000	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	70,000	175,407 (0%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	22 Feb 2022	1,375	176,782 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 30.00 per share.	22 Feb 2022	1,375	175,407 (0%)	0%	30	41,250	Common Stock
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	40,000	40,000	-		-	Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	22 Feb 2022	20,000	38,658 (0%)	0%		0	Common Stock
Ann M. Hanly	Chief Technology Officer		22 Feb 2022	47,000	47,000	-		-	Stock Option (Right to Buy)
Ann M. Hanly	Chief Technology Officer		22 Feb 2022	53,500	84,100 (0%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 31.93 per share.	17 Feb 2022	10,024	130,715 (0%)	0%	31.9	320,074	Common Stock
George A. Scangos	Director, President and CEO	Sale of securities on an exchange or to another person at price $ 30.65 per share.	17 Feb 2022	17,726	112,989 (0%)	0%	30.7	543,304	Common Stock
Howard Horn	CFO	Sale of securities on an exchange or to another person at price $ 31.93 per share.	17 Feb 2022	2,393	200,384 (0%)	0%	31.9	76,411	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 31.93 per share.	17 Feb 2022	2,293	105,407 (0%)	0%	31.9	73,218	Common Stock
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 31.93 per share.	17 Feb 2022	1,942	18,658 (0%)	0%	31.9	62,010	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 33.94 per share.	08 Feb 2022	1,375	107,700 (0%)	0%	33.9	46,668	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Feb 2022	1,375	220,880	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	08 Feb 2022	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	25 Jan 2022	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jan 2022	1,375	222,255	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 32.46 per share.	25 Jan 2022	1,375	107,700 (0%)	0%	32.5	44,633	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 37.39 per share.	18 Jan 2022	15,173	1,535,919 (1%)	0%	37.4	567,385	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 35.10 per share.	11 Jan 2022	1,375	107,700 (0%)	0%	35.1	48,263	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	11 Jan 2022	1,375	223,630	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	11 Jan 2022	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 39.95 per share.	28 Dec 2021	1,375	107,700 (0%)	0%	39.9	54,931	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	28 Dec 2021	1,375	225,005	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	28 Dec 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	20 Dec 2021	762,233	8,239,380 (7%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	20 Dec 2021	102,041	244,172 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	20 Dec 2021	987,767	10,677,283 (9%)	0%		0	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 54.35 per share.	20 Dec 2021	1,300	1,559,793 (1%)	0%	54.3	70,652	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 57.82 per share.	20 Dec 2021	2,401	1,551,092 (1%)	0%	57.8	138,826	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 56.10 per share.	20 Dec 2021	1,100	1,553,493 (1%)	0%	56.1	61,715	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 55.38 per share.	20 Dec 2021	5,200	1,554,593 (1%)	0%	55.4	287,993	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 51.87 per share.	20 Dec 2021	5,173	1,561,093 (1%)	0%	51.9	268,299	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	14 Dec 2021	2,750	110,450 (0%)	0%	1.5	4,208	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2021	2,750	226,380	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	14 Dec 2021	1,375	229,130	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	14 Dec 2021	2,750	107,700 (0%)	0%	50	137,500	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 45.88 per share.	14 Dec 2021	1,375	107,700 (0%)	0%	45.9	63,085	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	14 Dec 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	30 Nov 2021	15,125	122,825 (0%)	0%	1.5	23,141	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Nov 2021	15,125	230,505	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	30 Nov 2021	13,750	107,700 (0%)	0%	50	687,500	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 45.60 per share.	30 Nov 2021	1,375	121,450 (0%)	0%	45.6	62,700	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.76 per share.	30 Nov 2021	10,000	30,600 (0%)	0%	12.8	127,600	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Nov 2021	10,000	424,441	-		-	Employee Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 50.00 per share.	30 Nov 2021	10,000	20,600 (0%)	0%	50	500,000	Common Stock
Janet Napolitano	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 41.64 per share.	30 Nov 2021	1,435	4,809 (0%)	0%	41.6	59,753	Common Stock
Janet Napolitano	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Nov 2021	1,435	30,130	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Sale of securities on an exchange or to another person at price $ 46.25 per share.	30 Nov 2021	1,435	3,374 (0%)	0%	46.3	66,369	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	29 Nov 2021	217,781	9,001,613 (8%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	29 Nov 2021	29,153	142,131 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	29 Nov 2021	282,219	11,665,050 (10%)	0%		0	Common Stock
Ann M. Hanly	Chief Technology Officer		29 Nov 2021	11	11 (0%)	0%	45.5	500	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 36.80 per share.	26 Nov 2021	15,174	1,566,266 (1%)	0%	36.8	558,403	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Nov 2021	29,153	112,978 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Nov 2021	282,219	11,947,269 (10%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Nov 2021	217,781	9,219,394 (8%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 32.67 per share.	16 Nov 2021	1,375	107,700 (0%)	0%	32.7	44,921	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Nov 2021	1,375	245,630	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	16 Nov 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 36.94 per share.	02 Nov 2021	1,375	107,700 (0%)	0%	36.9	50,793	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2021	1,375	247,005	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	02 Nov 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 39.91 per share.	19 Oct 2021	8,503	1,581,440 (1%)	0%	39.9	339,340	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 39.12 per share.	19 Oct 2021	6,671	1,589,943 (1%)	0%	39.1	260,974	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 38.87 per share.	19 Oct 2021	1,375	107,700 (0%)	0%	38.9	53,446	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	19 Oct 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	19 Oct 2021	1,375	248,380	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 33.75 per share.	05 Oct 2021	1,375	107,700 (0%)	0%	33.7	46,406	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	05 Oct 2021	1,375	249,755	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	05 Oct 2021	1,375	109,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Sep 2021	8,000	251,130	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	22 Sep 2021	8,000	107,700 (0%)	0%	1.5	12,240	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	21 Sep 2021	4,125	99,700 (0%)	0%	50	206,250	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	21 Sep 2021	4,125	259,130	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	21 Sep 2021	4,125	103,825 (0%)	0%	1.5	6,311	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 53.06 per share.	17 Sep 2021	3,399	1,596,614 (1%)	0%	53.1	180,351	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 52.31 per share.	17 Sep 2021	11,775	1,600,013 (1%)	0%	52.3	615,950	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	07 Sep 2021	4,125	103,825 (0%)	0%	1.5	6,311	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	07 Sep 2021	4,125	263,255	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	07 Sep 2021	2,750	99,700 (0%)	0%	50	137,500	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 49.00 per share.	07 Sep 2021	1,375	102,450 (0%)	0%	49	67,375	Common Stock
Janet Napolitano	Director	Sale of securities on an exchange or to another person at price $ 51.15 per share.	30 Aug 2021	1,435	3,374 (0%)	0%	51.1	73,400	Common Stock
Janet Napolitano	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	30 Aug 2021	1,435	31,565	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 41.64 per share.	30 Aug 2021	1,435	4,809 (0%)	0%	41.6	59,753	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	25 Aug 2021	2,750	99,700 (0%)	0%	50	137,500	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	25 Aug 2021	2,750	102,450 (0%)	0%	1.5	4,208	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Aug 2021	2,750	267,380	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 48.00 per share.	24 Aug 2021	1,375	99,700 (0%)	0%	48	66,000	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Aug 2021	1,375	270,130	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	24 Aug 2021	1,375	101,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 50.00 per share.	23 Aug 2021	13,750	99,700 (0%)	0%	50	687,500	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Aug 2021	13,750	271,505	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	23 Aug 2021	13,750	113,450 (0%)	0%	1.5	21,038	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.76 per share.	23 Aug 2021	10,000	30,000 (0%)	0%	12.8	127,600	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Aug 2021	10,000	434,441	-		-	Employee Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 50.00 per share.	23 Aug 2021	10,000	20,000 (0%)	0%	50	500,000	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 45.52 per share.	19 Aug 2021	9,045	1,611,788 (1%)	0%	45.5	411,728	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 44.36 per share.	19 Aug 2021	6,129	1,620,833 (1%)	0%	44.4	271,882	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 41.00 per share.	10 Aug 2021	1,375	99,700 (0%)	0%	41	56,375	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Aug 2021	1,375	285,255	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	10 Aug 2021	1,375	101,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 36.72 per share.	27 Jul 2021	1,375	99,700 (0%)	0%	36.7	50,490	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Jul 2021	1,375	286,630	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	27 Jul 2021	1,375	101,075 (0%)	0%	1.5	2,104	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 37.84 per share.	19 Jul 2021	6,363	1,626,962 (1%)	0%	37.8	240,787	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 36.74 per share.	19 Jul 2021	8,811	1,633,325 (1%)	0%	36.7	323,722	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 35.56 per share.	15 Jul 2021	11,670	46,029 (0%)	0%	35.6	415,012	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	13 Jul 2021	1,375	288,005	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	13 Jul 2021	1,375	101,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 36.72 per share.	13 Jul 2021	1,375	99,700 (0%)	0%	36.7	50,490	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	01 Jul 2021	47,897	83,825 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	01 Jul 2021	1,742,248	9,437,175 (8%)	1%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	01 Jul 2021	2,257,752	12,229,488 (11%)	2%		0	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 45.23 per share.	01 Jul 2021	5,986	58,589 (0%)	0%	45.2	270,732	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 37.58 per share.	01 Jul 2021	2,348	36,030 (0%)	0%	37.6	88,243	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 36.63 per share.	01 Jul 2021	9,322	38,378 (0%)	0%	36.6	341,480	Common Stock
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 43.53 per share.	01 Jul 2021	1,671	47,700 (0%)	0%	43.5	72,739	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 46.22 per share.	01 Jul 2021	890	57,699 (0%)	0%	46.2	41,133	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 44.31 per share.	01 Jul 2021	4,794	64,575 (0%)	0%	44.3	212,405	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	29 Jun 2021	1,375	289,380	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 46.63 per share.	29 Jun 2021	1,375	99,700 (0%)	0%	46.6	64,116	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	29 Jun 2021	1,375	101,075 (0%)	0%	1.5	2,104	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.67 per share.	25 Jun 2021	3	20,003 (0%)	0%	12.7	38	Common Stock
Steven J. Rice	Chief Administrative Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	25 Jun 2021	3	444,441	-		-	Employee Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Sale of securities on an exchange or to another person at price $ 50.00 per share.	25 Jun 2021	3	20,000 (0%)	0%	50	150	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Jun 2021	8,000	290,755	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	23 Jun 2021	8,000	99,700 (0%)	0%	1.5	12,240	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Jun 2021	564,438	14,487,240 (13%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Jun 2021	435,562	11,179,423 (10%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	22 Jun 2021	11,974	35,928 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 46.75 per share.	21 Jun 2021	3,293	1,642,136 (1%)	0%	46.7	153,945	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 46.00 per share.	21 Jun 2021	11,881	1,645,429 (1%)	0%	46.0	546,570	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 43.95 per share.	17 Jun 2021	11,670	69,369 (0%)	0%	43.9	512,840	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	15 Jun 2021	1,375	93,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Jun 2021	1,375	298,755	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 45.29 per share.	15 Jun 2021	1,375	91,700 (0%)	0%	45.3	62,274	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 44.56 per share.	03 Jun 2021	11,670	81,039 (0%)	0%	44.6	520,033	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Jun 2021	1,375	300,130	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	01 Jun 2021	1,375	93,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 42.51 per share.	01 Jun 2021	1,375	91,700 (0%)	0%	42.5	58,451	Common Stock
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Elliott Sigal	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Phillip A. Sharp	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	108,742 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	27,328 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	92,709 (0%)	0%		0	Common Stock
Robert J. More	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Robert J. Perez	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Vicki L. Sato	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	1,657,310 (1%)	0%		0	Common Stock
Dipchand Nishar	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Dipchand Nishar	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Saira Ramasastry	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	6,748	6,748	-		-	Stock Option (Right to Buy)
Janet Napolitano	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	21 May 2021	3,374	3,374 (0%)	0%		0	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 44.77 per share.	20 May 2021	9,095	89,335 (0%)	0%	44.8	407,153	Common Stock
Robert J. More	Director	Sale of securities on an exchange or to another person at price $ 43.57 per share.	20 May 2021	2,575	98,430 (0%)	0%	43.6	112,198	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 43.35 per share.	19 May 2021	8,328	1,660,782 (1%)	0%	43.4	361,019	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 44.96 per share.	19 May 2021	1,443	1,653,936 (1%)	0%	45.0	64,877	Common Stock
Vicki L. Sato	Director	Sale of securities on an exchange or to another person at price $ 44.18 per share.	19 May 2021	5,403	1,655,379 (1%)	0%	44.2	238,705	Common Stock
Saira Ramasastry	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	19 May 2021	10,000	47,777	-		-	Stock Option (Right to Buy)
Saira Ramasastry	Director	Sale of securities on an exchange or to another person at price $ 43.73 per share.	19 May 2021	10,000	0 (0%)	0%	43.7	437,275	Common Stock
Saira Ramasastry	Director	Exercise or conversion of derivative security received from the company (such as an option) at price $ 12.76 per share.	19 May 2021	10,000	10,000 (0%)	0%	12.8	127,600	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 45.03 per share.	18 May 2021	1,375	91,700 (0%)	0%	45.0	61,916	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	18 May 2021	1,375	301,505	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	18 May 2021	1,375	93,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 46.03 per share.	04 May 2021	1,375	91,700 (0%)	0%	46.0	63,291	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 May 2021	1,375	302,880	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	04 May 2021	1,375	93,075 (0%)	0%	1.5	2,104	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 49.50 per share.	27 Apr 2021	7,900	91,700 (0%)	0%	49.5	391,077	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Apr 2021	7,900	304,255	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	27 Apr 2021	7,900	99,600 (0%)	0%	1.5	12,087	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 48.00 per share.	19 Apr 2021	2,340	91,700 (0%)	0%	48	112,320	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	19 Apr 2021	2,340	312,155	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	19 Apr 2021	2,340	94,040 (0%)	0%	1.5	3,580	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	16 Apr 2021	3,500	314,495	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	16 Apr 2021	3,500	91,700 (0%)	0%	1.5	5,355	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	13 Apr 2021	5,560	93,760 (0%)	0%	1.5	8,507	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	13 Apr 2021	5,560	317,995	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 43.57 per share.	13 Apr 2021	5,560	88,200 (0%)	0%	43.6	242,244	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	09 Apr 2021	14,000	88,200 (0%)	0%	1.5	21,420	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Apr 2021	14,000	323,555	-		-	Stock Option (Right to Buy)
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	217,781	11,832,766 (10%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	5,989	23,954 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	282,219	15,051,678 (13%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	217,781	11,614,985 (10%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	5,989	17,965 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	07 Apr 2021	282,219	15,333,897 (13%)	0%		0	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Apr 2021	2,315	37,037	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Apr 2021	4,629	4,630	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 51.40 per share.	01 Apr 2021	6,944	9,260 (0%)	0%	51.4	356,956	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.57 per share.	01 Apr 2021	2,315	16,204 (0%)	0%	1.6	3,646	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.48 per share.	01 Apr 2021	4,629	13,889 (0%)	0%	1.5	6,874	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	217,781	12,268,328 (11%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	282,219	15,898,335 (14%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	5,987	11,976 (0%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	282,219	15,616,116 (14%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	217,781	12,050,547 (10%)	0%		0	Common Stock
Robert Taylor Nelsen	Director, Ten Percent Owner	Other type of transaction at price $ 0.00 per share.	30 Mar 2021	5,989	5,989 (0%)	0%		0	Common Stock
Ann M. Hanly	Chief Technology Officer		29 Mar 2021	60,000	60,000	-		-	Employee Stock Option (Right to Buy)
Ann M. Hanly	Chief Technology Officer		29 Mar 2021	30,000	30,000 (0%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 53.60 per share.	23 Mar 2021	7,900	74,200 (0%)	0%	53.6	423,408	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Mar 2021	7,900	337,555	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	23 Mar 2021	7,900	82,100 (0%)	0%	1.5	12,087	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 48.00 per share.	10 Mar 2021	2,340	74,200 (0%)	0%	48	112,320	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Mar 2021	2,340	345,455	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	10 Mar 2021	2,340	76,540 (0%)	0%	1.5	3,580	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 44.80 per share.	09 Mar 2021	5,560	74,200 (0%)	0%	44.8	249,086	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Mar 2021	5,560	347,795	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	09 Mar 2021	5,560	79,760 (0%)	0%	1.5	8,507	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.58 per share.	01 Mar 2021	2,314	16,204 (0%)	0%	1.6	3,645	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Mar 2021	2,314	39,352	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Mar 2021	4,630	9,259	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 63.44 per share.	01 Mar 2021	6,944	9,260 (0%)	0%	63.4	440,531	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.49 per share.	01 Mar 2021	4,630	13,890 (0%)	0%	1.5	6,876	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	23 Feb 2021	18,900	82,100 (0%)	0%	1.5	28,917	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	23 Feb 2021	18,900	353,355	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 63.74 per share.	23 Feb 2021	7,900	74,200 (0%)	0%	63.7	503,577	Common Stock
George A. Scangos	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	111,000	4,609,559 (4%)	0%		0	Common Stock
George A. Scangos	Director, President and CEO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	222,000	222,000	-		-	Stock Option (Right to Buy)
Howard Horn	CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	50,000	50,000	-		-	Stock Option (Right to Buy)
Howard Horn	CFO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	25,000	202,777 (0%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	60,000	60,000	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	30,000	63,200 (0%)	0%		0	Common Stock
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	40,000	40,000	-		-	Stock Option (Right to Buy)
Steven J. Rice	Chief Administrative Officer	Grant, award, or other acquisition of securities at price $ 0.00 per share.	16 Feb 2021	20,000	20,000 (0%)	0%		0	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 71.16 per share.	09 Feb 2021	7,900	33,200 (0%)	0%	71.2	562,161	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	09 Feb 2021	7,900	372,255	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	09 Feb 2021	7,900	41,100 (0%)	0%	1.5	12,087	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.57 per share.	01 Feb 2021	4,630	229,166 (0%)	0%	1.6	7,292	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2021	4,630	41,666	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Feb 2021	2,314	13,889	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 69.91 per share.	01 Feb 2021	6,944	222,222 (0%)	0%	69.9	485,424	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.48 per share.	01 Feb 2021	2,314	224,536 (0%)	0%	1.5	3,436	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 48.17 per share.	26 Jan 2021	31,300	33,200 (0%)	0%	48.2	1,507,806	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	26 Jan 2021	31,300	380,155	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	26 Jan 2021	31,300	64,500 (0%)	0%	1.5	47,889	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 38.00 per share.	15 Jan 2021	10,530	33,200 (0%)	0%	38	400,140	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	15 Jan 2021	10,530	411,455	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	15 Jan 2021	10,530	43,730 (0%)	0%	1.5	16,111	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 29.36 per share.	12 Jan 2021	3,805	33,200 (0%)	0%	29.4	111,696	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	12 Jan 2021	3,805	421,985	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	12 Jan 2021	3,805	37,005 (0%)	0%	1.5	5,822	Common Stock
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 26.32 per share.	04 Jan 2021	6,945	222,222 (0%)	0%	26.3	182,795	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	04 Jan 2021	6,945	16,203	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.48 per share.	04 Jan 2021	6,945	229,167 (0%)	0%	1.5	10,313	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Dec 2020	9,500	425,790	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	24 Dec 2020	9,500	33,200 (0%)	0%	1.5	14,535	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	22 Dec 2020	3,805	435,290	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 31.19 per share.	22 Dec 2020	3,805	23,700 (0%)	0%	31.2	118,683	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	22 Dec 2020	3,805	27,505 (0%)	0%	1.5	5,822	Common Stock
Jeffrey S. Hatfield	Director	Grant, award, or other acquisition of securities at price $ 0.00 per share.	09 Dec 2020	46,500	46,500	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 31.27 per share.	08 Dec 2020	3,805	23,700 (0%)	0%	31.3	118,966	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	08 Dec 2020	3,805	439,095	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	08 Dec 2020	3,805	27,505 (0%)	0%	1.5	5,822	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.57 per share.	01 Dec 2020	2,315	229,167 (0%)	0%	1.6	3,646	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Dec 2020	2,315	46,296	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	01 Dec 2020	4,630	23,148	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 31.53 per share.	01 Dec 2020	6,945	222,222 (0%)	0%	31.5	218,968	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.49 per share.	01 Dec 2020	4,630	226,852 (0%)	0%	1.5	6,876	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 30.00 per share.	27 Nov 2020	2,930	23,700 (0%)	0%	30	87,900	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Nov 2020	2,930	442,900	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	27 Nov 2020	2,930	26,630 (0%)	0%	1.5	4,483	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 27.29 per share.	24 Nov 2020	2,340	23,700 (0%)	0%	27.3	63,848	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	24 Nov 2020	2,340	445,830	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	24 Nov 2020	2,340	26,040 (0%)	0%	1.5	3,580	Common Stock
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 26.26 per share.	10 Nov 2020	2,340	23,700 (0%)	0%	26.3	61,448	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	10 Nov 2020	2,340	448,170	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	10 Nov 2020	2,340	26,040 (0%)	0%	1.5	3,580	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2020	4,629	27,778	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	02 Nov 2020	2,315	48,611	-		-	Stock Option (Right to Buy)
Jay Parrish	Chief Business Officer	Sale of securities on an exchange or to another person at price $ 31.27 per share.	02 Nov 2020	6,944	222,222 (0%)	0%	31.3	217,153	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.57 per share.	02 Nov 2020	2,315	229,166 (0%)	0%	1.6	3,646	Common Stock
Jay Parrish	Chief Business Officer	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.48 per share.	02 Nov 2020	4,629	226,851 (0%)	0%	1.5	6,874	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share.	27 Oct 2020	3,805	450,510	-		-	Stock Option (Right to Buy)
Herbert Virgin	EVP, Research & CSO	Sale of securities on an exchange or to another person at price $ 35.04 per share.	27 Oct 2020	3,805	23,700 (0%)	0%	35.0	133,335	Common Stock
Herbert Virgin	EVP, Research & CSO	Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.53 per share.	27 Oct 2020	3,805	27,505 (0%)	0%	1.5	5,822	Common Stock

*All Values are in $ Million

Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc
Security Type: Share/ Warrants / Convertible Debentures

Data as reported to USA Exchanges

View All The Insider Trades disclosures

52.04% Fall from 52W High

High volume today

Insider Trading disclosures for Vir Biotechnology Inc

The latest disclosure was made by Vanina de Verneuil in Vir Biotechnology Inc where a trade of 7,373 Common Stock done at an average price of $9.1 was reported to US exchanges on Feb. 26, 2025.

Screeners based on Insider Trading and SAST parameters